N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

Base Information

Chemical Name:N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide
CAS No.:459842-48-9
Molecular Formula:C₂₆H₃₀N₂O₄S
Molecular Weight:466.601
Hs Code.:

Synonyms:N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

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Chemical Property of N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

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Technology Process of N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

There total 2 articles about N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 459841-26-0
3-methyl-4-[2-[N-isobutyl-N-(5-methyl-2-furylsulfonyl)amino]-4,5-5-dimethylphenoxymethyl]benzoic acid

: 459842-48-9
N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

Guidance literature:: 3-methyl-4-[2-[N-isobutyl-N-(5-methyl-2-furylsulfonyl)amino]-4,5-5-dimethylphenoxymethyl]benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; for 1h;

With ammonia; In water; at 0 ℃; for 0.0833333h;

With trifluorormethanesulfonic acid; In pyridine; at 0 ℃; for 0.833333h;

Reference yield:

: C₂₆H₃₂N₂O₅S

: 459842-48-9
N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

Guidance literature:: With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 0.833333h;

Reference yield:

: 459842-48-9
N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide

: 459842-49-0
N-[4,5-dimethyl-2-[2-methyl-4-(5-tetrazolyl)phenylmethyloxy]phenyl]-N-isobutyl-(5-methyl-2-furyl)sulfonylamide

Guidance literature:: N-[4,5-dimethyl-2-(2-methyl-4-cyanophenylmethyloxy)phenyl]-N-isobutyl-(5-methyl-2-furyl) sulfonylamide; With trimethyltin azide; at 20 ℃; for 31h; Heating / reflux; Neat (no solvent);

With hydrogenchloride; In methanol; water; for 2h;