C₄₉H₆₂O₄

Base Information

• Chemical Name: C₄₉H₆₂O₄
• CAS No.: 1370028-03-7
• Molecular Formula: C₄₉H₆₂O₄
• Molecular Weight: 715.029
• Mol file: 1370028-03-7.mol

Synonyms:C₄₉H₆₂O₄

Chemical Property of C₄₉H₆₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₆₂O₄

There total 5 articles about C₄₉H₆₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

6,6-dimethyl-1-vinylcyclohex-1-ene (18238-29-4) + C39H46O4 → C49H62O4 (1370028-03-7) + C49H62O4 (1370028-08-2)

Guidance literature:

With zinc(II) chloride; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1248/cpb.60.137

Reference yield:

C33H36O3 → C49H62O4 (1370028-03-7) + C49H62O4 (1370028-08-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / 0 °C / Inert atmosphere

1.2: 1 h / -78 °C / Inert atmosphere

2.1: toluene / 5 h / 120 °C / Inert atmosphere

3.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere

3.2: -78 °C / Inert atmosphere

4.1: Crabtree's catalyst; hydrogen / dichloromethane / 48 h / 20 °C / Inert atmosphere

5.1: trimethylaluminum / hexane; dichloromethane / 0.5 h / 0 °C / Inert atmosphere

5.2: 1 h / 0 °C / Inert atmosphere

6.1: tert.-butyl lithium / tetrahydrofuran; diethyl ether; pentane / 0.67 h / -78 °C / Inert atmosphere

6.2: 1.5 h / Inert atmosphere

7.1: zinc(II) chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

With n-butyllithium; Crabtree's catalyst; hydrogen; trimethylaluminum; tert.-butyl lithium; sodium hexamethyldisilazane; zinc(II) chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; toluene; pentane; 7.1: Diels-Alder reaction;

DOI:10.1248/cpb.60.137

Reference yield:

C33H36O3 (1370028-13-9) → C49H62O4 (1370028-03-7) + C49H62O4 (1370028-08-2)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere

1.2: -78 °C / Inert atmosphere

2.1: Crabtree's catalyst; hydrogen / dichloromethane / 48 h / 20 °C / Inert atmosphere

3.1: trimethylaluminum / hexane; dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3.2: 1 h / 0 °C / Inert atmosphere

4.1: tert.-butyl lithium / tetrahydrofuran; diethyl ether; pentane / 0.67 h / -78 °C / Inert atmosphere

4.2: 1.5 h / Inert atmosphere

5.1: zinc(II) chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

With Crabtree's catalyst; hydrogen; trimethylaluminum; tert.-butyl lithium; sodium hexamethyldisilazane; zinc(II) chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; pentane; 5.1: Diels-Alder reaction;

DOI:10.1248/cpb.60.137

upstream raw materials:

6,6-dimethyl-1-vinylcyclohex-1-ene

C₃₃H₃₆O₃

C₃₇H₄₂O₅

C₃₇H₄₄O₅

Downstream raw materials:

C₅₁H₇₀O₅