Mepixanox

Base Information

Chemical Name:Mepixanox
CAS No.:17854-59-0
Molecular Formula:C20H21NO3
Molecular Weight:323.392
Hs Code.:2934999090
European Community (EC) Number:241-810-6
UNII:7419T4YQQW
DSSTox Substance ID:DTXSID90170504
Nikkaji Number:J107.253F
Wikipedia:Mepixanox
Wikidata:Q6817820
NCI Thesaurus Code:C66094
Metabolomics Workbench ID:154373
ChEMBL ID:CHEMBL2104462
Mol file:17854-59-0.mol

Synonyms:3-methoxy-4-(piperidinomethyl)xanthone;mepixanox;pimexone;pimexone hydrochloride

Suppliers and Price of Mepixanox

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Mepixanox

Chemical Property:

Vapor Pressure:1.13E-09mmHg at 25°C
Melting Point:159-160°
Boiling Point:488°Cat760mmHg
PKA:8.33±0.10(Predicted)
Flash Point:249°C
PSA：42.68000
Density:1.224g/cm³
LogP:3.87860
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:323.15214353
Heavy Atom Count:24
Complexity:448

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3O2)CN4CCCCC4
Description Mepixanox is a respiratory stimulant useful in the treatment of chronic pneumopathy and other cardiorespiratory insufficiencies, including those induced by general anesthesia.

Technology Process of Mepixanox

There total 6 articles about Mepixanox which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 110-89-4
piperidine

: 27500-82-9
4-chloromethyl-3-methoxy-9H-xanthen-9-one

: 17854-59-0
mepixanox

Guidance literature:: In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield:

: 17854-59-0
mepixanox

Guidance literature:: Aus entspr. 4-Brommethylverb. m. Piperidin;

Reference yield:

: 150-19-6
O-methylresorcine

: 17854-59-0
mepixanox

Guidance literature:: Multi-step reaction with 4 steps

1: 82.7 percent / copper-bronze, copper(I) iodide, K₂CO₃ / dimethylformamide / 4 h / 140 °C

2: 101 g / conc. H₂SO₄ / 1 h / 50 °C

3: 9 g / AcOH, aq. HCl / 2 h / 60 °C

4: 89 percent / dimethylformamide / 2 h / Ambient temperature

With hydrogenchloride; copper(l) iodide; sulfuric acid; copper; potassium carbonate; acetic acid; In N,N-dimethyl-formamide;