2-hydroxy-2-methoxymethylcyclohexanone

Base Information

• Chemical Name: 2-hydroxy-2-methoxymethylcyclohexanone
• CAS No.: 78743-57-4
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.197
• Mol file: 78743-57-4.mol

Synonyms:2-hydroxy-2-methoxymethylcyclohexanone

Chemical Property of 2-hydroxy-2-methoxymethylcyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-hydroxy-2-methoxymethylcyclohexanone

There total 1 articles about 2-hydroxy-2-methoxymethylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1,2-bis(trimethylsilyloxy)cyclohex-1-ene (6838-67-1) + chloromethyl methyl ether (107-30-2) → 2-hydroxy-2-methoxymethylcyclohexanone (78743-57-4)

Guidance literature:

C₃H₇CuI; zinc; In dichloromethane; 1.) 0 deg C, 1 h, 2.) room temperature, 2 h;

DOI:10.1246/cl.1981.551

Reference yield: 75.0%

2-hydroxy-2-methoxymethylcyclohexanone (78743-57-4) → cycloheptane-1,3-dione (1194-18-9)

Guidance literature:

With potassium hydrogensulfate; at 170 - 180 ℃; under 20 - 25 Torr;

DOI:10.1246/cl.1981.551

upstream raw materials:

1,2-bis(trimethylsilyloxy)cyclohex-1-ene

chloromethyl methyl ether

Downstream raw materials:

cycloheptane-1,3-dione