N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride

Base Information

• Chemical Name: N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride
• CAS No.: 121249-40-9
• Molecular Formula: C₅₁H₆₂ClN₄O₁₃PS
• Molecular Weight: 1037.57
• Mol file: 121249-40-9.mol

Synonyms:N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride

Chemical Property of N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride

There total 2 articles about N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C45H58Cl2N3O11P → N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride (121249-40-9)

Guidance literature:

With oxalyl dichloride; In dichloromethane; for 0.5h;

DOI:10.1021/ja00198a052

Reference yield:

N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid chloride (121176-43-0) → N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid-4-nitrophenyl-thioester chloride (121249-40-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂ / 15 h / Ambient temperature

2: 86 percent / oxalic acid dichloride / CH₂Cl₂ / 0.5 h

With pyridine; oxalyl dichloride; In dichloromethane;

DOI:10.1021/ja00198a052

upstream raw materials:

N-(Triphenylphosphonioethoxycarbonyl)-L-valyl-L-lactoyl-L-valyl-L-lactoyl-L-valyl-L-lactic acid chloride