Technology Process of C27H25BrN2O6
There total 3 articles about C27H25BrN2O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(S)-methyl 1-formyl-1-[1,2-hydrazinedicarboxylic acid-bis(phenylmethyl)ester]-2,3-dihydro-1H-indene-5-carboxylate;
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene;
In
tetrahydrofuran; water; tert-butyl alcohol;
at 4 ℃;
for 12h;
diazomethyl-trimethyl-silane;
In
methanol; diethyl ether; toluene;
DOI:10.1021/ol0512942
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 75 percent / (R)-proline / acetonitrile / 4 h
2.1: NaH2PO4; 2-methyl-2-butene; NaClO2 / 2-methyl-propan-2-ol; H2O; tetrahydrofuran / 12 h / 4 °C
2.2: 81 percent / toluene; methanol; diethyl ether
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; D-Prolin;
In
tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
DOI:10.1021/ol0512942
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 95 percent / tBuOK / tetrahydrofuran / -20 - 20 °C
2.1: 75 percent / (R)-proline / acetonitrile / 4 h
3.1: NaH2PO4; 2-methyl-2-butene; NaClO2 / 2-methyl-propan-2-ol; H2O; tetrahydrofuran / 12 h / 4 °C
3.2: 81 percent / toluene; methanol; diethyl ether
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; potassium tert-butylate; D-Prolin;
In
tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
1.1: Wittig olefination;
DOI:10.1021/ol0512942
![(S)-methyl 1-formyl-1-[1,2-hydrazinedicarboxylic acid-bis(phenylmethyl)ester]-2,3-dihydro-1H-indene-5-carboxylate](/Databaselist/images/loading.webp)
