(R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide

Base Information

Chemical Name:(R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide
CAS No.:1374823-95-6
Molecular Formula:C₂₅H₄₃N₃O₂S
Molecular Weight:449.701
Hs Code.:

Synonyms:(R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide

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Technology Process of (R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide

There total 2 articles about (R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 1374823-92-3
C₂₀H₃₅N₃O₂S

: 111-30-8,29257-65-6,79215-57-9
Glutaraldehyde

: 1374823-95-6
(R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide

Guidance literature:: C₂₀H₃₅N₃O₂S; Glutaraldehyde; In acetonitrile; at 20 ℃; for 0.25h;

With sodium cyanoborohydride; In acetonitrile; at 20 ℃; for 0.25h;

With acetic acid; In acetonitrile; at 20 ℃;
DOI:10.1021/ja3026196

Reference yield:

: 592507-77-2
(R)-(+)-2,4,6-triisopropylphenylsulfinamide

: 1374823-95-6
(R)-2,4,6-triisopropyl-N-((2-methyl-2-(piperidin-1-yl)propyl)carbamoyl)benzenesulfinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydride / tetrahydrofuran / 0 °C

1.2: 1 h / 20 °C

2.1: acetonitrile / 0.25 h / 20 °C

2.2: 0.25 h / 20 °C

2.3: 20 °C

With potassium hydride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/ja3026196