(2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Base Information

Chemical Name:(2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol
CAS No.:174198-74-4
Molecular Formula:C₂₈H₄₀O₅Si
Molecular Weight:484.708
Hs Code.:

Synonyms:(2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Suppliers and Price of (2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

There total 11 articles about (2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 58479-61-1
tert-butylchlorodiphenylsilane

: 174198-73-3
(2R,3S,6S)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-hydroxymethyl-6-methyl-tetrahydro-pyran-3-ol

: 174198-74-4
(2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1016/0040-4039(95)02132-9

Reference yield:

: 35334-60-2
(E)-6-acetoxy-4-methyl-4-hexenal

: 174198-74-4
(2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Guidance literature:: Multi-step reaction with 11 steps

1: 69 percent / benzene / Heating

2: 84 percent / K₂CO₃ / methanol / 0 deg C to RT

3: 92 percent / TsOH / diethyl ether / 0 deg C to RT

4: 83 percent / DIBAH / toluene / -65 °C

5: 98 percent / t-BuOOH, D-(-)-DIPT, Ti(O-iPr)4, 4 Angstroem molecular sieves / CH₂Cl₂ / -23 °C

6: 92 percent / Ti(O-iPr)4 / CH₂Cl₂ / 0 deg C to RT

7: 86 percent / Dowex (50W-X₂) / methanol / Ambient temperature

8: 1.) t-BuOOH, D-(-)-DIPT, Ti(O-iPr)4, 4 Angstroem molecular sieves, 2.) CSA / 1.) CH₂Cl₂, -23 deg C, 2.) CH₂Cl₂, RT

9: p-TsOH / acetone / Ambient temperature

10: K₂CO₃ / ethanol / Ambient temperature

11: 100 percent / imidazole / dimethylformamide / Ambient temperature

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; 4 A molecular sieve; Dowex (50W-X₂); camphor-10-sulfonic acid; diisobutylaluminium hydride; potassium carbonate; D-(-)-diisopropyl tartrate; toluene-4-sulfonic acid; In methanol; diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene; benzene;
DOI:10.1016/0040-4039(95)02132-9

Reference yield:

: 110965-85-0
(2E,6E)-8-Hydroxy-6-methyl-octa-2,6-dienoic acid methyl ester

: 174198-74-4
(2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol

Guidance literature:: Multi-step reaction with 9 steps

1: 92 percent / TsOH / diethyl ether / 0 deg C to RT

2: 83 percent / DIBAH / toluene / -65 °C

3: 98 percent / t-BuOOH, D-(-)-DIPT, Ti(O-iPr)4, 4 Angstroem molecular sieves / CH₂Cl₂ / -23 °C

4: 92 percent / Ti(O-iPr)4 / CH₂Cl₂ / 0 deg C to RT

5: 86 percent / Dowex (50W-X₂) / methanol / Ambient temperature

6: 1.) t-BuOOH, D-(-)-DIPT, Ti(O-iPr)4, 4 Angstroem molecular sieves, 2.) CSA / 1.) CH₂Cl₂, -23 deg C, 2.) CH₂Cl₂, RT

7: p-TsOH / acetone / Ambient temperature

8: K₂CO₃ / ethanol / Ambient temperature

9: 100 percent / imidazole / dimethylformamide / Ambient temperature

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; 4 A molecular sieve; Dowex (50W-X₂); camphor-10-sulfonic acid; diisobutylaluminium hydride; potassium carbonate; D-(-)-diisopropyl tartrate; toluene-4-sulfonic acid; In methanol; diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1016/0040-4039(95)02132-9