((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane

Base Information

• Chemical Name: ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane
• CAS No.: 1020736-06-4
• Molecular Formula: C₂₁H₃₉BrOSi
• Molecular Weight: 415.53
• Mol file: 1020736-06-4.mol

Synonyms:((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane

Chemical Property of ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane

There total 1 articles about ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,3R)-1-(tert-butyldimethylsilyloxy)-3-((E)-5-hydroxy-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexane (1020736-04-2) → ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane (1020736-06-4)

Guidance literature:

With phosphorus tribromide; In diethyl ether; at 0 ℃; for 0.166667h;

DOI:10.1021/ol800326n

Reference yield: 78.0%

C22H32O2S (1020736-08-6) + ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane (1020736-06-4) → C42H68O3SSi (1020736-10-0)

Guidance literature:

C₂₂H₃₂O₂S; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h; Inert atmosphere;

((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane; In tetrahydrofuran; hexane; for 4h; Inert atmosphere;

DOI:10.1021/ol800326n

Reference yield:

7-hydroxy-2H-chromen-2-one (93-35-6) + ((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane (1020736-06-4) → C30H44O4Si (1020735-93-6)

Guidance literature:

7-hydroxy-2H-chromen-2-one; With potassium carbonate; In acetone;

((1S,3R)-3-((E)-5-bromo-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexyloxy)(tert-butyl)dimethylsilane; In acetone; at 20 ℃; for 12h;

DOI:10.1021/ol800326n

upstream raw materials:

(1S,3R)-1-(tert-butyldimethylsilyloxy)-3-((E)-5-hydroxy-3-methylpent-3-enyl)-2,2-dimethyl-4-methylenecyclohexane

Downstream raw materials:

C₄₂H₆₈O₃SSi

C₃₀H₄₄O₄Si