5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester

Base Information

Chemical Name:5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester
CAS No.:1061457-72-4
Molecular Formula:C₂₆H₃₄BrN₃O₂
Molecular Weight:500.479
Hs Code.:

Synonyms:5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester

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Technology Process of 5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester

There total 1 articles about 5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 64137-52-6
N-methyl-N-[3-(2-benzimidazolyl)propyl]amine

: 1061284-73-8
methyl isopropyl(3-bromopropyl)-4-bromophenylacetate

: 1061457-72-4
5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester

Guidance literature:: With potassium carbonate; In ethanol; for 3h; Reflux;

Reference yield: 88.0%

: 1061457-72-4
5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester

: 1552303-58-8
C₂₅H₃₂BrN₃O₂

Guidance literature:: 5-{[3-(1H-benzimidazole-2-yl)propyl]methylamino}-2-(4-bromophenyl)-2-isopropylpentanoic acid methyl ester; With sodium hydroxide; In methanol; water; at 60 ℃; for 2h;

With hydrogenchloride; In methanol; water;
DOI:10.1016/j.bmcl.2013.12.078