(E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester

Base Information

• Chemical Name: (E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester
• CAS No.: 154224-44-9
• Molecular Formula: C₁₆H₁₆O₅S
• Molecular Weight: 320.366
• Mol file: 154224-44-9.mol

Synonyms:(E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester

Chemical Property of (E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester

There total 1 articles about (E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-2-(3-acetoxyprop-1-enyl)furan (118813-17-5) + methyl benzenesulfonylacetate (34097-60-4) → (E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester (154224-44-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; triphenylphosphine; Yield given. Multistep reaction; 1) THF, 5 min, room temperature; 2) THF, reflux, overnight;

DOI:10.1039/P19930002395

Reference yield:

(E)-2-Benzenesulfonyl-5-furan-2-yl-pent-4-enoic acid methyl ester (154224-44-9) → Toluene-4-sulfonic acid (E)-5-furan-2-yl-pent-4-enyl ester (154224-34-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 62 percent / 6percent Na-Hg, Na₂HPO₄ / methanol / 1.5 h / 0 - 5 °C

2: 98 percent / LiAlH₄ / diethyl ether / Ambient temperature

3: 100 percent / pyridine / 16 h / 0 °C

With pyridine; disodium hydrogenphosphate; lithium aluminium tetrahydride; sodium amalgam; In methanol; diethyl ether;

DOI:10.1039/P19930002395

upstream raw materials:

(E)-2-(3-acetoxyprop-1-enyl)furan

methyl benzenesulfonylacetate

Downstream raw materials:

Toluene-4-sulfonic acid (E)-5-furan-2-yl-pent-4-enyl ester