1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

Base Information

Chemical Name:1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane
CAS No.:748185-87-7
Molecular Formula:C₄₄H₄₄F₂N₆O₄
Molecular Weight:758.868
Hs Code.:

Synonyms:1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

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Chemical Property of 1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

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Technology Process of 1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

There total 3 articles about 1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 124050-15-3
2-(chloromethyl)-6-fluoroquinoline

: 162148-45-0
1,4,7,10-tetraaza-cyclododecane-1,7-dicarboxylic acid dibenzyl ester

: 748185-86-6
1,7-bis(benzyloxycarbonyl)-4-(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

: 748185-87-7
1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

Guidance literature:: With sodium hydrogencarbonate; In acetonitrile; at 40 ℃; for 48h;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 748185-87-7
1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

Guidance literature:: Multi-step reaction with 2 steps

1: 14 percent / NaHCO₃ / acetonitrile / 48 h / 40 °C

With sodium hydrogencarbonate; In acetonitrile;

Reference yield:

: 294-90-6
1,4,7,10-tetraazacyclododecan

: 748185-87-7
1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane

Guidance literature:: Multi-step reaction with 2 steps

1: 14 percent / NaHCO₃ / acetonitrile / 48 h / 40 °C

With sodium hydrogencarbonate; In acetonitrile;