1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol

Base Information

Chemical Name:1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol
CAS No.:57316-01-5
Molecular Formula:C₁₈H₁₉NO₂
Molecular Weight:281.354
Hs Code.:
ChEMBL ID:CHEMBL77756
DSSTox Substance ID:DTXSID60561763
Nikkaji Number:J394.911G
Wikidata:Q82445623
Mol file:57316-01-5.mol

Synonyms:57316-01-5;1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol;CHEMBL77756;SCHEMBL11387860;DTXSID60561763;RVYVGPUXVJZGKV-UHFFFAOYSA-N;1'-methyl-4-hydroxyxanthene-9-spiro-4'-piperidine

Suppliers and Price of 1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol

Chemical Property:

PSA：32.70000
LogP:3.44750
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:281.141578849
Heavy Atom Count:21
Complexity:377

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2(CC1)C3=C(C(=CC=C3)O)OC4=CC=CC=C24

Technology Process of 1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol

There total 8 articles about 1-Methylspiro[piperidine-4,9'-xanthen]-4'-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 92-83-1
xanthene

: 57316-01-5
4-hydroxy-1'-methylxanthene-9-spiro-4'-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaH, DMSO / tetrahydrofuran

With sodium hydride; dimethyl sulfoxide; In tetrahydrofuran;
DOI:10.1021/jm00130a022

Reference yield:

: 57315-99-8
9,9-bis(2-hydroxyethyl)xanthene

: 57316-01-5
4-hydroxy-1'-methylxanthene-9-spiro-4'-piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / pyridine / a) 0 to 5 deg C, 1 h, b) r.t., overnight

2: ethanol / Heating

With pyridine; In ethanol;
DOI:10.1021/jm00130a022

Reference yield:

: 55-86-7
mechlorethamine hydrochloride

: 57316-01-5
4-hydroxy-1'-methylxanthene-9-spiro-4'-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaH, DMSO / tetrahydrofuran

With sodium hydride; dimethyl sulfoxide; In tetrahydrofuran;
DOI:10.1021/jm00130a022