C₅₃H₅₈O₉

Base Information

• Chemical Name: C₅₃H₅₈O₉
• CAS No.: 364068-86-0
• Molecular Formula: C₅₃H₅₈O₉
• Molecular Weight: 839.038
• Mol file: 364068-86-0.mol

Synonyms:C₅₃H₅₈O₉

Chemical Property of C₅₃H₅₈O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₅₃H₅₈O₉

There total 7 articles about C₅₃H₅₈O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

carbonic acid tert-butyl ester 2-iodophenyl ester (364068-85-9) + C42H46O6 (364068-84-8) → C53H58O9 (364068-86-0)

Guidance literature:

With copper(l) iodide; triethylamine; triphenylphosphine; palladium diacetate; at 70 ℃; for 6h;

DOI:10.1002/chem.200305284

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C53H58O9 (364068-86-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / K₂CO₃; DMAP; [18]crown-6 / tetrahydrofuran / 1 h / 20 °C

2: 80 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

With dmap; copper(l) iodide; 18-crown-6 ether; potassium carbonate; triethylamine; triphenylphosphine; palladium diacetate; In tetrahydrofuran;

DOI:10.1002/chem.200305284

Reference yield:

carbonic acid tert-butyl ester 2-tert-butyl-6-iodo-4-[(triisopropylsilanyl)-ethynyl]-phenyl ester (364068-82-6) → C53H58O9 (364068-86-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 98 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

2: 0.82 g / tetrabutylammonium fluoride / CH₂Cl₂; tetrahydrofuran / 0.25 h / 20 °C

3: CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

4: 1.29 g / tetrabutylammonium fluoride / CH₂Cl₂; tetrahydrofuran

5: 80 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

With copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; palladium diacetate; In tetrahydrofuran; dichloromethane;

DOI:10.1002/chem.200305284

upstream raw materials:

carbonic acid tert-butyl ester 2-iodophenyl ester

C₄₂H₄₆O₆

2-Iodophenol

di-tert-butyl dicarbonate

Refernces