1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Base Information

Chemical Name:1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride
CAS No.:1427555-52-9
Molecular Formula:C₁₈H₁₇ClN₄O₂*ClH
Molecular Weight:393.273
Hs Code.:

Synonyms:1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Suppliers and Price of 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

There total 5 articles about 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1427555-50-7
ethyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylate

: 1427555-52-9
1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Guidance literature:: ethyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylate; With lithium hydroxide monohydrate; water; In tetrahydrofuran; for 3h;

With hydrogenchloride; In water; pH=1;

Reference yield:

: 416852-78-3
ethyl 1-[(3-aminopyridin-4-yl)methyl]piperidine-4-carboxylate

: 1427555-52-9
1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid; sodium nitrite / water / 0.08 h / 0 °C

2.1: pyridine; copper diacetate / 1,2-dichloro-ethane

3.1: lithium hydroxide / water; tetrahydrofuran / 3 h

3.2: pH 1

With pyridine; copper diacetate; acetic acid; lithium hydroxide; sodium nitrite; In tetrahydrofuran; water; 1,2-dichloro-ethane;

Reference yield:

: 55279-29-3
3-amino-pyridine-4-carbaldehyde

: 1427555-52-9
1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium tris(acetoxy)borohydride / dichloromethane / 0.08 h / 60 °C / Microwave irradiation

2.1: acetic acid; sodium nitrite / water / 0.08 h / 0 °C

3.1: pyridine; copper diacetate / 1,2-dichloro-ethane

4.1: lithium hydroxide / water; tetrahydrofuran / 3 h

4.2: pH 1

With pyridine; copper diacetate; sodium tris(acetoxy)borohydride; acetic acid; lithium hydroxide; sodium nitrite; In tetrahydrofuran; dichloromethane; water; 1,2-dichloro-ethane;