Asiminecin

Base Information

Chemical Name:Asiminecin
CAS No.:156256-35-8
Molecular Formula:C₃₇H₆₆O₇
Molecular Weight:622.927
Hs Code.:
Wikidata:Q105345061
Mol file:156256-35-8.mol

Synonyms:asiminecin

Suppliers and Price of Asiminecin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Asiminecin

Chemical Property:

Boiling Point:763.2±40.0 °C(Predicted)
PKA:14.45±0.20(Predicted)
PSA：105.45000
Density:1.054±0.06 g/cm3(Predicted)
LogP:7.85790
XLogP3:9.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:25
Exact Mass:622.48085444
Heavy Atom Count:44
Complexity:801

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(CCCCC(C1CCC(O1)C2CCC(O2)C(CCCCCCCCCCCCC3=CC(OC3=O)C)O)O)O

Technology Process of Asiminecin

There total 23 articles about Asiminecin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 193949-23-4
(S)-3-[(R)-13-{(2R,5R,2'R,5'R)-5'-[(1R,6S)-1,6-Bis-(2-trimethylsilanyl-ethoxymethoxy)-undecyl]-octahydro-[2,2']bifuranyl-5-yl}-13-(2-trimethylsilanyl-ethoxymethoxy)-tridecyl]-5-methyl-5H-furan-2-one

: 156256-35-8
(S)-3-{(R)-13-[(2R,5R,2'R,5'R)-5'-((1R,6S)-1,6-Dihydroxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-13-hydroxy-tridecyl}-5-methyl-5H-furan-2-one

Guidance literature:: With pyridinium p-toluenesulfonate; In ethanol; at 75 ℃; for 16h;
DOI:10.1021/jo970424k

Reference yield:

: 163277-83-6
(2E)-6-((tert-butyldimethylsilyl)oxy)hex-2-enal

: 156256-35-8
(S)-3-{(R)-13-[(2R,5R,2'R,5'R)-5'-((1R,6S)-1,6-Dihydroxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-13-hydroxy-tridecyl}-5-methyl-5H-furan-2-one

Guidance literature:: Multi-step reaction with 18 steps

2: 75 percent / pyridine / 1.) 0 deg C, 30 min, 2.) room temperature, 18 h

3: 76 percent / TBAF / tetrahydrofuran / 12 h / 50 °C

4: 1.) NaH / 1.) THF, room temperature, 30 min, 2.) 40 min

5: 85 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂ / -78 - 20 °C

6: 81 percent / InCl₃ / ethyl acetate

7: 94 percent / i-Pr₂NEt

8: 90 percent / H₂ / Rh/Al₂O₃

9: 94 percent / TBAF

10: 84 percent / Et₃N, DMAP

11: 94 percent / pyridine

12: 83 percent / LiEt₃BH

13: 95 percent / TBAF

14: (COCl)2, DMSO, Et₃N

15: 75 percent / CrCl₂

16: 74 percent / Pd(PPh₃)2Cl₂, Et₂NH, CuI

17: 80 percent / TsNHNH₂, NaOAc

18: 80 percent / PPTS / ethanol / 16 h / 75 °C

With pyridine; chromium dichloride; dmap; indium(III) chloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxalyl dichloride; tetrabutyl ammonium fluoride; hydrogen; sodium acetate; pyridinium p-toluenesulfonate; sodium hydride; lithium triethylborohydride; dimethyl sulfoxide; diethylamine; triethylamine; N-ethyl-N,N-diisopropylamine; toluene-4-sulfonic acid hydrazide; Rh/Al₂O₃; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate;
DOI:10.1021/jo970424k

Reference yield:

: 177854-08-9
4(R),5(R)-bis(tert-butyldimethylsilyl)oxyoctadialdehyde

: 156256-35-8
(S)-3-{(R)-13-[(2R,5R,2'R,5'R)-5'-((1R,6S)-1,6-Dihydroxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-13-hydroxy-tridecyl}-5-methyl-5H-furan-2-one

Guidance literature:: Multi-step reaction with 18 steps

2: 75 percent / pyridine / 1.) 0 deg C, 30 min, 2.) room temperature, 18 h

3: 76 percent / TBAF / tetrahydrofuran / 12 h / 50 °C

4: 1.) NaH / 1.) THF, room temperature, 30 min, 2.) 40 min

5: 85 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂ / -78 - 20 °C

6: 81 percent / InCl₃ / ethyl acetate

7: 94 percent / i-Pr₂NEt

8: 90 percent / H₂ / Rh/Al₂O₃

9: 94 percent / TBAF

10: 84 percent / Et₃N, DMAP

11: 94 percent / pyridine

12: 83 percent / LiEt₃BH

13: 95 percent / TBAF

14: (COCl)2, DMSO, Et₃N

15: 75 percent / CrCl₂

16: 74 percent / Pd(PPh₃)2Cl₂, Et₂NH, CuI

17: 80 percent / TsNHNH₂, NaOAc

18: 80 percent / PPTS / ethanol / 16 h / 75 °C

With pyridine; chromium dichloride; dmap; indium(III) chloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxalyl dichloride; tetrabutyl ammonium fluoride; hydrogen; sodium acetate; pyridinium p-toluenesulfonate; sodium hydride; lithium triethylborohydride; dimethyl sulfoxide; diethylamine; triethylamine; N-ethyl-N,N-diisopropylamine; toluene-4-sulfonic acid hydrazide; Rh/Al₂O₃; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate;
DOI:10.1021/jo970424k