N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine

Base Information

• Chemical Name: N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine
• CAS No.: 514225-45-7
• Molecular Formula: C₁₈H₂₁N₃O₃
• Molecular Weight: 327.383
• Mol file: 514225-45-7.mol

Synonyms:N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine

Chemical Property of N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine

There total 1 articles about N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

N1-(2-nitrophenyl)propane-1,3-diamine (145315-42-0) + hydrocinnamic acid chloride (645-45-4) → N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine (514225-45-7)

Guidance literature:

With sodium hydroxide; In chloroform; for 0.25h;

DOI:10.1055/s-2002-35980

Reference yield:

N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine (514225-45-7) → 10-benzyl-3,4-dihydro-2H-1,4a,9-triaza-phenanthrene 9-oxide

Guidance literature:

Multi-step reaction with 2 steps

1: trimethylsilyl polyphoshate / CH₂Cl₂ / 5 h / Heating

2: CHCl₃ / 96 h / 20 °C

With trimethylsilyl polyphoshate; In dichloromethane; chloroform;

DOI:10.1055/s-2002-35980

Reference yield:

N-(o-nitrophenyl)-N'-(3-phenylpropionyl)-1,3-propanediamine (514225-45-7) → 1-(o-nitrophenyl)-2-(2-phenylethyl)-1,4,5,6-tetrahydropyrimidine (514225-53-7)

Guidance literature:

With trimethylsilyl polyphoshate; In dichloromethane; for 5h; Heating;

DOI:10.1055/s-2002-35980

upstream raw materials:

N₁-(2-nitrophenyl)propane-1,3-diamine

hydrocinnamic acid chloride

Downstream raw materials:

1-(o-nitrophenyl)-2-(2-phenylethyl)-1,4,5,6-tetrahydropyrimidine