2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester

Base Information

• Chemical Name: 2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester
• CAS No.: 328933-54-6
• Molecular Formula: C₄₈H₅₈N₂O₁₃
• Molecular Weight: 870.994

Synonyms:2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester

Chemical Property of 2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester

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Technology Process of 2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester

There total 2 articles about 2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

→ 2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester (328933-54-6)

Guidance literature:

Reference yield:

→ 2,3,4-Triacetyl-{1-O-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-2-[4-(2, 2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic Acid Methyl Ester (328933-53-5) + 2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester (328933-54-6)

Guidance literature:

Reference yield: 40.0%

2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester (328933-54-6) → Bazedoxifene O5-glucuronide

Guidance literature:

2,3,4-triacetyl-{1-O-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-[4-(2,2-dimethyl-propionyloxy)-phenyl]-3-methyl-1H-indol-5-yl}-glucuronic acid methyl ester; With methanol; lithium hydroxide; water; In 1,4-dioxane; at 20 - 65 ℃; for 1.5h;

With acetic acid; In 1,4-dioxane;

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