2-Amino-2-methylsuccinic acid

Base Information

Chemical Name:2-Amino-2-methylsuccinic acid
CAS No.:3227-17-6
Deprecated CAS:866-73-9
Molecular Formula:C₅H₉NO₄
Molecular Weight:147.131
Hs Code.:2922499990
NSC Number:14963,153559
UNII:70W4HTK6W3
Nikkaji Number:J347.993E
Wikidata:Q27896228
Mol file:3227-17-6.mol

Synonyms:2-methylaspartic acid;2-methylaspartic acid, (DL-Asp)-isomer;2-methylaspartic acid, (L-Asp)-isomer;alpha-methyl-DL-aspartate

Suppliers and Price of 2-Amino-2-methylsuccinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemPep
α-Me-Asp-OH
1g
$ 726.00

ChemPep
α-Me-Asp-OH
5g
$ 1778.00

American Custom Chemicals Corporation
(S)-(+)-2-AMINO-2-METHYL BUTANEDIOIC ACID 95.00%
250MG
$ 727.65

American Custom Chemicals Corporation
(S)-(+)-2-AMINO-2-METHYL BUTANEDIOIC ACID 95.00%
2.5G
$ 2136.75

AK Scientific
alpha-Me-Asp-OH
1g
$ 1815.00

AHH
alpha-Methyl-L-Asp 99%
0.25g
$ 298.00

Total 14 raw suppliers

Chemical Property of 2-Amino-2-methylsuccinic acid

Chemical Property:

Vapor Pressure:0.00395mmHg at 25°C
Refractive Index:1.4210 (estimate)
Boiling Point:259.2°C at 760 mmHg
PKA:2.32±0.28(Predicted)
Flash Point:110.6°C
PSA：100.62000
Density:1.4285 (rough estimate)
LogP:-0.03660
XLogP3:-3.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:147.05315777
Heavy Atom Count:10
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

α-Me-Asp-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC(=O)O)(C(=O)O)N

Technology Process of 2-Amino-2-methylsuccinic acid

There total 20 articles about 2-Amino-2-methylsuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: ((2R,4S)-3-Benzyl-4-methyl-5-oxo-2-phenyl-oxazolidin-4-yl)-acetic acid ethyl ester

: 3227-17-6
L-α-methylaspartic acid

Guidance literature:: In hydrogen bromide; for 3h; Heating;
DOI:10.1016/S0040-4039(00)96091-X

Reference yield: 94.6%

: 103825-52-1
2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1,4-dimethyl-5-oxoimidazolidin-4-yl>essigsaeure

: 3227-17-6
L-α-methylaspartic acid

Guidance literature:: With hydrogen bromide; at 180 ℃; for 4h;
DOI:10.1002/hlca.19850680603

Reference yield: 91.0%

: 1266681-10-0
methyl 2-[(3S,5aR,6aS,7aS)-2,3,5,5a,6,6a,7,7a-octahydro-3,6,6,7a-tetramethyl-2-oxobicyclo[4.1.0]hept-1⁽⁶⁾eno[3,4-b][1,4]oxazin-3-yl]acetate

: 3227-17-6
L-α-methylaspartic acid

Guidance literature:: methyl 2-[(3S,5aR,6aS,7aS)-2,3,5,5a,6,6a,7,7a-octahydro-3,6,6,7a-tetramethyl-2-oxobicyclo[4.1.0]hept-1⁽⁶⁾eno[3,4-b][1,4]oxazin-3-yl]acetate; With cesium hydroxide; water; at 70 ℃; for 3h;

With hydrogenchloride; In water;
DOI:10.1021/jo1022537