furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

Base Information

Chemical Name:furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide
CAS No.:943776-57-6
Molecular Formula:C₂₇H₂₃N₅O₃S
Molecular Weight:497.577
Hs Code.:

Synonyms:furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

Suppliers and Price of furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

There total 6 articles about furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 943771-02-6
N'-(3-cyano-6-isopropyl-pyridin-2-yl)-N,N-dimethyl-formamidine

: 943776-60-1
furan-2-carboxylic acid [3-amino-4-(4-hydroxy-phenylsulfanyl)phenyl]-amide

: 943776-57-6
furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

Guidance literature:: In acetic acid; at 120 ℃; for 0.166667h;

Reference yield:

: 563-80-4
3-methyl-butan-2-one

: 943776-57-6
furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium / diethyl ether / 0 - 20 °C

2.1: water / 0.17 h / 20 °C

2.2: 2 h / Heating / reflux

2.3: pH 4

3.1: tetrabutylammomium bromide; phosphorus pentoxide / toluene / 5 h / Heating / reflux

4.1: ammonia / ethanol / 20 h / 130 °C

5.1: toluene / 3 h / Heating / reflux

6.1: acetic acid / 0.17 h / 120 °C

With tetrabutylammomium bromide; ammonia; sodium; phosphorus pentoxide; In diethyl ether; ethanol; water; acetic acid; toluene;

Reference yield:

: 55793-14-1
4-methyl-3-oxo-pentanal; sodium enolate

: 943776-57-6
furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide

Guidance literature:: Multi-step reaction with 5 steps

1.1: water / 0.17 h / 20 °C

1.2: 2 h / Heating / reflux

1.3: pH 4

2.1: tetrabutylammomium bromide; phosphorus pentoxide / toluene / 5 h / Heating / reflux

3.1: ammonia / ethanol / 20 h / 130 °C

4.1: toluene / 3 h / Heating / reflux

5.1: acetic acid / 0.17 h / 120 °C

With tetrabutylammomium bromide; ammonia; phosphorus pentoxide; In ethanol; water; acetic acid; toluene;