(2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid

Base Information

Chemical Name:(2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid
CAS No.:1042275-15-9
Molecular Formula:C₃₃H₅₁NO₅Si₂
Molecular Weight:597.943
Hs Code.:

Synonyms:(2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid

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Technology Process of (2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid

There total 1 articles about (2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₃H₅₁NO₄Si₂

: 1042275-15-9
(2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 20 ℃; for 6h;
DOI:10.1021/jm070680h

Reference yield: 44.0%

: 1042275-15-9
(2R)-4-(tert-butyldimethylsilanyloxy)-4-[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-ylcarbamoyl]-5-phenylpentanoic acid

: 1187976-09-5
3-amino-5-(methanesulfonyl(methyl)amino)-N-((R)-1-phenylethyl)benzamide

: 1187975-94-5
(R)-2-benzyl-2-(tert-butyldimethylsilanyloxy)pentanedioic acid 1-{[(1S,2R)-2-(tert-butyldimethylsilanyloxy)indan-1-yl]amide} 5-{[3-(methanesulfonyl(methyl)amino)-5-((R)-1-phenylethylcarbamoyl)phenyl]amide}

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 50 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.bmcl.2009.06.065