1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

Base Information

Chemical Name:1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea
CAS No.:1227780-15-5
Molecular Formula:C₂₂H₂₇N₉O₃
Molecular Weight:465.515
Hs Code.:

Synonyms:1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

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Chemical Property of 1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

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Technology Process of 1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

There total 1 articles about 1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2-azidoethanamine trifluoroacetic acid salt

: 918106-28-2
1-(tert-butyl)-3-(6-(3,5-dimethoxyphenyl)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7-yl)urea

: 1227780-15-5
1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 50 ℃; for 24h; Inert atmosphere;
DOI:10.1039/b923882d

Reference yield: 88.0%

: 7223-38-3
N,N-Dimethylpropargylamin

: 1227780-15-5
1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

: 1227780-17-7
1-tert-butyl-3-(6-(3,5-dimethoxyphenyl)-2-(2-(4-((dimethylamino)methyl)-1H-1,2,3-triazol-1-yl)ethylamino)pyrido[2,3-d]pyrimidin-7-yl)urea

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; In water; tert-butyl alcohol; at 20 ℃; for 20h;
DOI:10.1039/b923882d

Reference yield: 85.0%

: 1227780-15-5
1-(2-(2-azidoethylamino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea

: 927-74-2
3-Butyn-1-ol

: 1227780-19-9
1-tert-butyl-3-(6-(3,5-dimethoxyphenyl)-2-(2-(4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl)ethylamino)pyrido[2,3-d]pyrimidin-7-yl)urea

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; In water; tert-butyl alcohol; at 20 ℃; for 20h;
DOI:10.1039/b923882d