4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide

Base Information

• Chemical Name: 4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide
• CAS No.: 1268495-36-8
• Molecular Formula: C₂₀H₁₈N₈O₂S₂
• Molecular Weight: 466.547
• Mol file: 1268495-36-8.mol

Synonyms:4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide

Chemical Property of 4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide

There total 1 articles about 4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

picolinic acid hydrazide (1452-63-7) + 1 ,4-phenylenediisothiocyanate (4044-65-9) → 4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide (1268495-36-8)

Guidance literature:

In ethanol; for 0.08h; Reflux;

DOI:10.1080/10426507.2010.480949

Reference yield: 90.0%

4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide (1268495-36-8) → 2,2-(1,4-phenylendiamine)bis-5-(2-pyridyl)-1,3,4-thiadiazole (1268495-39-1)

Guidance literature:

With sulfuric acid; at 0 - 20 ℃; for 8h;

DOI:10.1080/10426507.2010.480949

Reference yield: 87.0%

4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide (1268495-36-8) → 4,4-(1,4-phenylene)bis-5-(2-pyridyl)-1,2,4-triazole-3-thiol

Guidance literature:

4,4-(1,4-phenylene)bis-1-(2-picolinoyl)-thiosemicarbazide; With sodium hydroxide; In water; for 1h; Reflux;

With hydrogenchloride; In water; for 1h; Reflux;

DOI:10.1080/10426507.2010.480949

upstream raw materials:

picolinic acid hydrazide

1 ,4-phenylenediisothiocyanate

Downstream raw materials:

2,2-(1,4-phenylendiamine)bis-5-(2-pyridyl)-1,3,4-thiadiazole

4,4-(1,4-phenylene)bis-[(3-methylthio)-5-(2-pyridyl)-1,2,4-triazole]