4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester

Base Information

• Chemical Name: 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester
• CAS No.: 469904-14-1
• Molecular Formula: C₂₂H₁₇NO₄
• Molecular Weight: 359.381
• Mol file: 469904-14-1.mol

Synonyms:4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester

Chemical Property of 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester

There total 4 articles about 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Monomethyl terephthalate (1679-64-7) → 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester (469904-14-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: SOCl₂

1.2: AlCl₃ / 25 °C

2.1: 74 percent / H₂SO₄; CrO₃ / acetic acid / 5 - 20 °C

3.1: dimethylformamide; oxalyl chloride / CH₂Cl₂ / 2 h / 20 °C

4.1: CH₂Cl₂ / 20 °C

With chromium(VI) oxide; thionyl chloride; oxalyl dichloride; sulfuric acid; N,N-dimethyl-formamide; In dichloromethane; acetic acid; 1.2: Friedel-Crafts acylation;

DOI:10.1002/1521-4184(200203)335:2/3<83::AID-ARDP83>3.0.CO;2-3

Reference yield:

(4-(methoxycarbonyl)phenyl)(4-methylphenyl)methanone (64141-11-3) → 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester (469904-14-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 74 percent / H₂SO₄; CrO₃ / acetic acid / 5 - 20 °C

2: dimethylformamide; oxalyl chloride / CH₂Cl₂ / 2 h / 20 °C

3: CH₂Cl₂ / 20 °C

With chromium(VI) oxide; oxalyl dichloride; sulfuric acid; N,N-dimethyl-formamide; In dichloromethane; acetic acid;

DOI:10.1002/1521-4184(200203)335:2/3<83::AID-ARDP83>3.0.CO;2-3

Reference yield:

toluene (108-88-3,15644-74-3,16713-13-6) → 4-(4-(phenylaminocarbonyl)benzoyl)benzoic acid methyl ester (469904-14-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: SOCl₂

1.2: AlCl₃ / 25 °C

2.1: 74 percent / H₂SO₄; CrO₃ / acetic acid / 5 - 20 °C

3.1: dimethylformamide; oxalyl chloride / CH₂Cl₂ / 2 h / 20 °C

4.1: CH₂Cl₂ / 20 °C

With chromium(VI) oxide; thionyl chloride; oxalyl dichloride; sulfuric acid; N,N-dimethyl-formamide; In dichloromethane; acetic acid; 1.2: Friedel-Crafts acylation;

DOI:10.1002/1521-4184(200203)335:2/3<83::AID-ARDP83>3.0.CO;2-3

upstream raw materials:

aniline

Monomethyl terephthalate

(4-(methoxycarbonyl)phenyl)(4-methylphenyl)methanone

toluene