Technology Process of Benzyl O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-2,3-di-O-benzyl-6-O-(4-methoxyphenyl)-β-D-galactopyranoside
There total 17 articles about Benzyl O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-2,3-di-O-benzyl-6-O-(4-methoxyphenyl)-β-D-galactopyranoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetra-(n-butyl)ammonium iodide; sodium hydrogencarbonate; thiourea;
In
tetrahydrofuran;
at 55 ℃;
DOI:10.1039/b006981g
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: BF3*Et2O / CH2Cl2 / 12 h / 20 °C
2.1: 12.4 g / NaOMe; MeOH / 2 h
3.1: 12.4 g / CSA / CHCl3 / 1 h / Heating
4.1: NaH / dimethylformamide / 0.5 h / 20 °C
4.2: 16.8 g / Bu4NI / dimethylformamide
5.1: 13.6 g / PTSA; propane-1,3-diol / CH2Cl2; methanol / 96 h / Heating
6.1: pyridine / 6 h / 20 °C
7.1: NaH / dimethylformamide
7.2: 3.37 g / dimethylformamide / 16 h
8.1: 63 percent / NIS; TESOTf / CH2Cl2 / -20 °C
9.1: 85 percent / NaHCO3; thiourea; Bu4NI / tetrahydrofuran / 55 °C
With
pyridine; methanol; N-iodo-succinimide; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; triethylsilyl trifluoromethyl sulfonate; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; thiourea; trimethyleneglycol;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
DOI:10.1039/b006981g
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: pyridine / 6 h / 20 °C
2.1: NaH / dimethylformamide
2.2: 3.37 g / dimethylformamide / 16 h
3.1: 63 percent / NIS; TESOTf / CH2Cl2 / -20 °C
4.1: 85 percent / NaHCO3; thiourea; Bu4NI / tetrahydrofuran / 55 °C
With
pyridine; N-iodo-succinimide; triethylsilyl trifluoromethyl sulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium hydrogencarbonate; thiourea;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b006981g