Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Base Information

Chemical Name:Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester
CAS No.:192462-78-5
Molecular Formula:C₂₆H₂₆BrCl₆NO₈
Molecular Weight:773.116
Hs Code.:

Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Synonyms:Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Suppliers and Price of Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

There total 5 articles about Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 188583-18-8
4,6-di-O-benzyl-2-deoxy-3-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside

: 192462-78-5
Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Guidance literature:: With dibromo sulfoxide; In dichloromethane; N,N-dimethyl-formamide; for 2h; Ambient temperature;
DOI:10.1248/cpb.45.312

Reference yield:

: 129253-51-6
allyl 2-deoxy-3-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside

: 192462-78-5
Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / CF₃SO₃H / CH₂Cl₂; cyclohexane / 20 h / Ambient temperature

2: 1.) 1,5-cyclooctadienebis(methyldiphenylphosphine)iridium hexafluorophosphate, 2.) I₂, pyridine, H₂O / 1.) THF, 50 deg C, 2 h, 2.) THF, RT, 30 min

3: SOBr₂ / CH₂Cl₂; dimethylformamide / 2 h / Ambient temperature

With pyridine; dibromo sulfoxide; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; trifluorormethanesulfonic acid; water; iodine; In dichloromethane; cyclohexane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.312

Reference yield:

: 188583-14-4
allyl-2-N-Troc-2-deoxy-α-D-glucopyranoside

: 192462-78-5
Carbonic acid (2R,3S,4R,5R)-3-benzyloxy-2-benzyloxymethyl-6-bromo-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 2,2,2-trichloro-ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 94 percent / p-TsOH / dimethylformamide / 18 h / Ambient temperature

2: 75 percent / 4-dimethylaminopyridine, pyridine / CH₂Cl₂ / 20 h / Ambient temperature

3: 94 percent / 68percent aq. AcOH / 5 h / Ambient temperature

4: 98 percent / CF₃SO₃H / CH₂Cl₂; cyclohexane / 20 h / Ambient temperature

5: 1.) 1,5-cyclooctadienebis(methyldiphenylphosphine)iridium hexafluorophosphate, 2.) I₂, pyridine, H₂O / 1.) THF, 50 deg C, 2 h, 2.) THF, RT, 30 min

6: SOBr₂ / CH₂Cl₂; dimethylformamide / 2 h / Ambient temperature

With pyridine; dmap; dibromo sulfoxide; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; trifluorormethanesulfonic acid; water; iodine; toluene-4-sulfonic acid; acetic acid; In dichloromethane; cyclohexane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.312