N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Base Information

Chemical Name:N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester
CAS No.:128217-80-1
Molecular Formula:C₃₁H₃₄N₂O₉
Molecular Weight:578.619
Hs Code.:

Synonyms:N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Suppliers and Price of N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

There total 3 articles about N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 128217-70-9
N-[2-(3,4-Bis-benzyloxy-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

: 128217-80-1
N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Guidance literature:: With nitric acid; In acetic acid; at 0 ℃; for 2h;
DOI:10.1021/jo00301a008

Reference yield:

: 63-84-3,90638-38-3
dopa

: 128217-80-1
N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / 48 h / Ambient temperature

2: 1.) NaHCO₃, 2.) K₂CO₃, NaI / 1.) water, THF, overnight, 2.) ethanol, reflux, 4 h

3: 88 percent / nitric acid (d = 1.4) / acetic acid / 2 h / 0 °C

With thionyl chloride; nitric acid; sodium hydrogencarbonate; potassium carbonate; sodium iodide; In acetic acid;
DOI:10.1021/jo00301a008

Reference yield:

: 23234-41-5
L-Dopa ethyl ester hydrochloride

: 128217-80-1
N-[2-(4,5-Bis-benzyloxy-2-nitro-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaHCO₃, 2.) K₂CO₃, NaI / 1.) water, THF, overnight, 2.) ethanol, reflux, 4 h

2: 88 percent / nitric acid (d = 1.4) / acetic acid / 2 h / 0 °C

With nitric acid; sodium hydrogencarbonate; potassium carbonate; sodium iodide; In acetic acid;
DOI:10.1021/jo00301a008