Technology Process of 3-[(dimethylamino)methyl]-5-fluorobenzaldehyde
There total 3 articles about 3-[(dimethylamino)methyl]-5-fluorobenzaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
manganese(IV) oxide;
In
chloroform;
at 80 ℃;
for 7h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: dibenzoyl peroxide; N-Bromosuccinimide; tetrachloromethane / 4 h / Reflux
2: dichloromethane; tetrahydrofuran / 2 h / 60 °C / sealed vessel
3: lithium aluminium tetrahydride / diethyl ether; tetrahydrofuran / 1.5 h / 20 °C / Cooling with ice
4: manganese(IV) oxide / chloroform / 7 h / 80 °C
With
tetrachloromethane; manganese(IV) oxide; N-Bromosuccinimide; lithium aluminium tetrahydride; dibenzoyl peroxide;
In
tetrahydrofuran; diethyl ether; dichloromethane; chloroform;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / diethyl ether; tetrahydrofuran / 1.5 h / 20 °C / Cooling with ice
2: manganese(IV) oxide / chloroform / 7 h / 80 °C
With
manganese(IV) oxide; lithium aluminium tetrahydride;
In
tetrahydrofuran; diethyl ether; chloroform;
