Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester
• CAS No.: 59980-96-0
• Molecular Formula: C₃₅H₃₅F₃O₈S
• Molecular Weight: 672.719
• Mol file: 59980-96-0.mol

Synonyms:Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester

Chemical Property of Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester

There total 1 articles about Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside (38184-10-0) + benzenesulfenyl triflate (84224-65-7) → Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester (59980-96-0)

Guidance literature:

With 2,6-di-tert-butyl-4-methylpyridine; In diethyl ether; at -78 ℃; for 0.0833333h;

DOI:10.1021/ja9734814

Reference yield:

1-adamanthanol (768-95-6) + Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester (59980-96-0) → 1-adamantyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside

Guidance literature:

In dichloromethane; at -78 - -20 ℃; for 0.666667h; Yield given;

DOI:10.1021/ja9734814

Reference yield:

methyl 3α-(ethoxycarbonyloxy)-7α-(hydroxyl)-5β-cholanoate (61252-49-1) + Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester (59980-96-0) → (R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3-Ethoxycarbonyloxy-10,13-dimethyl-7-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester

Guidance literature:

In diethyl ether; at -78 - -20 ℃; for 0.666667h; Yield given;

DOI:10.1021/ja9734814

upstream raw materials:

phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside

benzenesulfenyl triflate

Downstream raw materials:

1-O-2,6-dimethylphenyl-2,3,4,6-tetra-O-benzyl-α,β-D-glucopyranose

2',6'-dimethylphenyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside