1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline

Base Information

Chemical Name:1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline
CAS No.:121306-60-3
Molecular Formula:C₁₅H₁₃N₃O
Molecular Weight:251.288
Hs Code.:
DSSTox Substance ID:DTXSID30923758
Pharos Ligand ID:BJ7PLSNQYHDG
ChEMBL ID:CHEMBL4452678

Synonyms:1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline;5-Phenyl-1-(4-pyridinylcarbonyl)-4,5-dihydro-1H-pyrazole;CHEMBL4452678;1H-Pyrazole, 4,5-dihydro-5-phenyl-1-(4-pyridinylcarbonyl)-;121306-60-3;SCHEMBL9380451;DTXSID30923758;BDBM50513026;LS-128458;(5-Phenyl-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl)methanone

Suppliers and Price of 1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline

Chemical Property:

Vapor Pressure:1.57E-07mmHg at 25°C
Boiling Point:428°C at 760 mmHg
Flash Point:212.6°C
Density:1.21g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:251.105862047
Heavy Atom Count:19
Complexity:343

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C=NN(C1C2=CC=CC=C2)C(=O)C3=CC=NC=C3

Technology Process of 1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline

There total 3 articles about 1-(4-Pyridylcarbonyl)-5-phenyl-2-pyrazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 55-22-1
pyridine-4-carboxylic acid

: 936-47-0
5-phenyl-4,5-dihydro-1H-pyrazole

: 121306-60-3
(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl)methanone

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dimethyl sulfoxide;
DOI:10.1021/acs.jmedchem.9b00318

Reference yield:

: 14371-10-9
(E)-3-phenylpropenal

: 121306-60-3
(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / tert-butyl alcohol / Reflux

2: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide

With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; hydrazine; In dimethyl sulfoxide; tert-butyl alcohol;
DOI:10.1021/acs.jmedchem.9b00318