N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester

Base Information

• Chemical Name: N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester
• CAS No.: 100325-00-6
• Molecular Formula: C₅₂H₆₂N₂O₂₁
• Molecular Weight: 1051.07
• Mol file: 100325-00-6.mol

Synonyms:N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester

Chemical Property of N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester

There total 3 articles about N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (2S,3R)-2-(benzyloxycarbonyl)amino-3-hydroxybutanoate (72289-51-1) → N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester (100325-00-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / AgClO₄, molecular sieve / toluene; CH₂Cl₂ / -50 °C

2: 1.) H₂S, (C₂H₅)3N / 1.) pyridine, water, 25 h, room temperature, 2.) 22 h, room temperature

With molecular sieve; hydrogen sulfide; silver perchlorate; triethylamine; In dichloromethane; toluene;

Reference yield:

2-azido-4,6-di-O-benzoyl-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyl bromide (87376-57-6) → N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester (100325-00-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / AgClO₄, molecular sieve / toluene; CH₂Cl₂ / -50 °C

2: 1.) H₂S, (C₂H₅)3N / 1.) pyridine, water, 25 h, room temperature, 2.) 22 h, room temperature

With molecular sieve; hydrogen sulfide; silver perchlorate; triethylamine; In dichloromethane; toluene;

Reference yield:

acetic anhydride (108-24-7) + N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester → N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester (100325-00-6)

Guidance literature:

With hydrogen sulfide; triethylamine; Yield given. Multistep reaction; 1.) pyridine, water, 25 h, room temperature, 2.) 22 h, room temperature;

upstream raw materials:

acetic anhydride

tert-butyl (2S,3R)-2-(benzyloxycarbonyl)amino-3-hydroxybutanoate

2-azido-4,6-di-O-benzoyl-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyl bromide

Downstream raw materials:

O-<(2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin

N-(Benzyloxacarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin

O-<(2,3,4,6-Tetra-O-acetyl-β-galactopyranosyl)-(1<*>3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-threonin-tert-butylester

Refernces