tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate

Base Information

• Chemical Name: tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate
• CAS No.: 475278-48-9
• Molecular Formula: C₁₇H₂₆N₄O₄
• Molecular Weight: 350.418
• Mol file: 475278-48-9.mol

Synonyms:tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate

Chemical Property of tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate

There total 1 articles about tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-ethyl-2-nitro-5-(1-piperazinyl)aniline (475278-47-8) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate (475278-48-9)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water;

Reference yield:

tert-butyl 4-[3-(ethylamino)-4-nitrophenyl]-1-piperazinecarboxylate (475278-48-9) + CHCl3/MeOH → tert-butyl 4-[4-amino-3-(ethylamino)phenyl]-1-piperazinecarboxylate (475278-49-0)

Guidance literature:

With ammonia; hydrazine hydrate; In tetrahydrofuran; ethanol;

upstream raw materials:

N-ethyl-2-nitro-5-(1-piperazinyl)aniline

di-tert-butyl dicarbonate

Downstream raw materials:

tert-butyl 4-[4-amino-3-(ethylamino)phenyl]-1-piperazinecarboxylate