(R_S,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid

Base Information

• Chemical Name: (R_S,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid
• CAS No.: 477587-02-3
• Molecular Formula: C₁₆H₂₅NO₄S
• Molecular Weight: 327.445

Synonyms:(R_S,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid

Chemical Property of (R_S,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid

Chemical Property:

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Technology Process of (R_S,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid

There total 2 articles about (R_S,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(RS,2S,3R)-(-)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid 4-methoxybenzyl ester → (RS,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid (477587-02-3)

Guidance literature:

With methoxybenzene; trifluoroacetic acid; for 0.25h;

DOI:10.1021/jo025957u

Reference yield: 78.0%

(RS,2S,3R)-(-)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid methyl ester (477586-86-0) → (RS,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid (477587-02-3)

Guidance literature:

With bis(tri-n-butyltin)oxide; In toluene; for 24h; Heating;

DOI:10.1021/jo025957u

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (RS,2S,3R)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid (477587-02-3) → (RS,2S,3R)-(-)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid methyl ester (477586-86-0)

Guidance literature:

DOI:10.1021/jo025957u

upstream raw materials:

(R_S,2S,3R)-(-)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid methyl ester

Downstream raw materials:

(R_S,2S,3R)-(-)-2-(4-methoxybenzyl)-3-(2-methylpropane-2-sulfinylamino)butyric acid methyl ester

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