(4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

Base Information

Chemical Name:(4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide
CAS No.:948052-65-1
Molecular Formula:C₂₈H₄₇N₃O₂S
Molecular Weight:489.766
Hs Code.:

Synonyms:(4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

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Chemical Property of (4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

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Technology Process of (4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

There total 4 articles about (4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₃H₅₅N₃O₄S

: 948052-65-1
(4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

Guidance literature:: With trifluoroacetic acid;
DOI:10.1016/j.bmcl.2007.05.059

Reference yield:

: 948052-48-0
C₁₇H₂₂N₂O₅S

: 948052-65-1
(4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

Guidance literature:: Multi-step reaction with 2 steps

1: EDCI; HOBt; Et₃N / CH₂Cl₂

2: TFA

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2007.05.059

Reference yield:

: 122-85-0
para-acetamidobenzaldehyde

: 948052-65-1
(4R)-2-(4-acetylamino-phenyl)-thiazolidine-4-carboxylic acid hexadecylamide

Guidance literature:: Multi-step reaction with 4 steps

1: EtOH; H₂O / 20 °C

2: aq. NaOH / dioxane

3: EDCI; HOBt; Et₃N / CH₂Cl₂

4: TFA

With sodium hydroxide; ethanol; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmcl.2007.05.059