tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane

Base Information

• Chemical Name: tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane
• CAS No.: 1322546-79-1
• Molecular Formula: C₁₈H₂₈O₃SSi
• Molecular Weight: 352.57
• Mol file: 1322546-79-1.mol

Synonyms:tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane

Chemical Property of tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane

There total 2 articles about tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-phenylsulfonylacetate (7605-30-3) → tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane (1322546-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C

1.2: 4 h / 0 - 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C

3.1: 1H-imidazole / N,N-dimethyl-formamide / 15 h / 20 °C

With 1H-imidazole; lithium aluminium tetrahydride; lithium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2013.02.015

Reference yield:

1-benzenesulfonyl-cyclopent-3-enecarboxylic ethyl ester (1322546-74-6) → tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane (1322546-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 15 h / 20 °C

With 1H-imidazole; lithium aluminium tetrahydride; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2013.02.015

Reference yield:

tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane (1322546-79-1) → C18H30O4SSi (1322546-81-5)

Guidance literature:

tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane; With borane-THF; In tetrahydrofuran; at 0 ℃; for 1.41667h;

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 1h;

DOI:10.1016/j.tetasy.2013.02.015

upstream raw materials:

ethyl 2-phenylsulfonylacetate

1-benzenesulfonyl-cyclopent-3-enecarboxylic ethyl ester

Downstream raw materials:

(S)-3-(hydroxymethyl)-1-cyclopentanone

C₁₃H₁₄O₃

C₄₃H₅₈N₂O₅

tert-butyl (5R,7S)-2,2-dimethyl-7-{1-methyl-5-[5-(4-methylphenyl)pentanoyl]-1H-pyrrol-2-yl}-3-oxa-1-azaspiro[4.4]nonane-1-carboxylate