Technology Process of methyl N-benzyloxycarbonyl-3-O-benzyl-2,6-dideoxy-2,6-imino-α-D-mannofuranoside
There total 12 articles about methyl N-benzyloxycarbonyl-3-O-benzyl-2,6-dideoxy-2,6-imino-α-D-mannofuranoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridine / CH2Cl2; pyridine / 0.25 h / -30 °C
2: sodium azide / dimethylformamide / 24 h / 50 °C
3: 80 percent / sodium metoxide / methanol / 6 h / Ambient temperature
4: 95 percent / p-toluenesulphonyl chloride / pyridine / 12 h / 0 °C
5: 1.) hydrogen / 1.) palladium black / 1.) ethanol, 12 h, room temp., 2.) 50 deg C, 12 h
6: aq. sodium bicarbonate / diethyl ether / 2 h / Ambient temperature
With
pyridine; sodium azide; hydrogen; sodium methylate; sodium hydrogencarbonate; p-toluenesulfonyl chloride;
palladium;
In
pyridine; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)90034-1
- Guidance literature:
-
Multi-step reaction with 7 steps
1: acid resin (Dowex 50W-XH) / methanol / 12 h / Heating
2: pyridine / CH2Cl2; pyridine / 0.25 h / -30 °C
3: sodium azide / dimethylformamide / 24 h / 50 °C
4: 80 percent / sodium metoxide / methanol / 6 h / Ambient temperature
5: 95 percent / p-toluenesulphonyl chloride / pyridine / 12 h / 0 °C
6: 1.) hydrogen / 1.) palladium black / 1.) ethanol, 12 h, room temp., 2.) 50 deg C, 12 h
7: aq. sodium bicarbonate / diethyl ether / 2 h / Ambient temperature
With
pyridine; sodium azide; acid resin (Dowex 50W-XH); hydrogen; sodium methylate; sodium hydrogencarbonate; p-toluenesulfonyl chloride;
palladium;
In
pyridine; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)90034-1
- Guidance literature:
-
Multi-step reaction with 9 steps
1: hydrochloric acid / methanol; H2O / 20 h / Ambient temperature
2: sodium methoxide / 3 h / Heating
3: acid resin (Dowex 50W-XH) / methanol / 12 h / Heating
4: pyridine / CH2Cl2; pyridine / 0.25 h / -30 °C
5: sodium azide / dimethylformamide / 24 h / 50 °C
6: 80 percent / sodium metoxide / methanol / 6 h / Ambient temperature
7: 95 percent / p-toluenesulphonyl chloride / pyridine / 12 h / 0 °C
8: 1.) hydrogen / 1.) palladium black / 1.) ethanol, 12 h, room temp., 2.) 50 deg C, 12 h
9: aq. sodium bicarbonate / diethyl ether / 2 h / Ambient temperature
With
pyridine; hydrogenchloride; sodium azide; acid resin (Dowex 50W-XH); hydrogen; sodium methylate; sodium hydrogencarbonate; p-toluenesulfonyl chloride;
palladium;
In
pyridine; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)90034-1
