(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate

Base Information

Chemical Name:(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate
CAS No.:1220703-52-5
Molecular Formula:C₄₈H₅₂F₁₀N₂O₉
Molecular Weight:990.933
Hs Code.:

(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate

Synonyms:(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate

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Chemical Property of (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate

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Technology Process of (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate

There total 1 articles about (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32315-10-9
bis(trichloromethyl) carbonate

: 1220703-22-9
tert-butyl {(1S,2R)-2-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-1-methylethyl}{[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}carbamate

: 130972-89-3
(4-hydroxy-3-methoxybenzyl)carbamic acid tert-butyl ester

: 1220703-52-5
(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl-4-{[(tert-butoxycarbonyl)amino]methyl}-2-methoxyphenylcarbonate

Guidance literature:: bis(trichloromethyl) carbonate; (4-hydroxy-3-methoxybenzyl)carbamic acid tert-butyl ester; With pyridine; In dichloromethane; at 0 - 25 ℃; Inert atmosphere;

tert-butyl {(1S,2R)-2-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-1-methylethyl}{[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}carbamate; With pyridine; In dichloromethane; at 25 ℃;