N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

Base Information

Chemical Name:N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide
CAS No.:1158176-29-4
Molecular Formula:C₂₈H₃₂N₂O₄
Molecular Weight:460.573
Hs Code.:

N<sup>1</sup>,N<sup>3</sup>-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N<sup>1</sup>,N<sup>3</sup>-dimethylisophthalamide

Synonyms:N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

Suppliers and Price of N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

Chemical Property:

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Technology Process of N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

There total 1 articles about N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 299-42-3,7009-81-6,90-83-5,6912-63-6
ephedrine

: 99-63-8
benzene-1,3-dicarbonyl dichloride

: 1158176-29-4
N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 8h;
DOI:10.3987/COM-08-11583

Reference yield:

: 3099-28-3
2,6-bis(chloromethyl)pyridine

: 1158176-29-4
N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

: 1158176-36-3
C₃₅H₃₇N₃O₄

Guidance literature:: N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

2,6-bis(chloromethyl)pyridine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.3987/COM-08-11583

Reference yield:

: 1158176-29-4
N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide

: 626-16-4
3-(chloromethyl)benzyl chloride

: 1158176-35-2
C₃₆H₃₈N₂O₄

Guidance literature:: N¹,N³-bis((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N¹,N³-dimethylisophthalamide; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

3-(chloromethyl)benzyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.3987/COM-08-11583