2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine

Base Information

• Chemical Name: 2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine
• CAS No.: 554452-10-7
• Molecular Formula: C₁₅H₁₄ClN₃O₂S
• Molecular Weight: 335.814

Synonyms:2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine

Chemical Property of 2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine

Chemical Property:

Purity/Quality:

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Technology Process of 2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine

There total 2 articles about 2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

t-Butyl {2-{1-[(2-Chloro-benzene)sulfonyl]-1H-pyrrolo[3,2-b]pyridin-3-yl}ethyl}carbamate (554453-21-3) → 2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine (554452-10-7)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; methanol;

Reference yield:

2-Chloro-3-nitropyridine (5470-18-8,34515-82-7) + cyanoacetic acid tert-butyl ester (1116-98-9) + p-toluenesulfonic acid monohydrate (6192-52-5) → 2-[1-(2-chlorobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethylamine (554452-10-7)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; dichloromethane; water; toluene;

upstream raw materials:

2-Chloro-3-nitropyridine

cyanoacetic acid tert-butyl ester

p-toluenesulfonic acid monohydrate

t-Butyl {2-{1-[(2-Chloro-benzene)sulfonyl]-1H-pyrrolo[3,2-b]pyridin-3-yl}ethyl}carbamate

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