1-Methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine

Base Information

Chemical Name:1-Methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine
CAS No.:891856-25-0
Molecular Formula:C₁₃H₁₉N₃O₃
Molecular Weight:265.312
Hs Code.:
DSSTox Substance ID:DTXSID701246953

Synonyms:1-methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine;SCHEMBL3207509;DTXSID701246953;891856-25-0

Suppliers and Price of 1-Methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:265.14264148
Heavy Atom Count:19
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCN(CC1)CCOC2=CC=CC(=C2)[N+](=O)[O-]

Technology Process of 1-Methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine

There total 2 articles about 1-Methyl-4-[2-(3-nitrophenoxy)ethyl]piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 109-01-3
1-methyl-piperazine

: 87291-34-7
1-(2-chloroethoxy)-3-nitrobenzene

: 891856-25-0
1-methyl-4-(2-(3-nitrophenoxy)ethyl)piperazine

Guidance literature:: With tetra-(n-butyl)ammonium iodide; potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b01765

Reference yield:

: 554-84-7
meta-nitrophenol

: 891856-25-0
1-methyl-4-(2-(3-nitrophenoxy)ethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C

2: tetrahydrofuran / 12 h / 60 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;