KS IV

Base Information

• Chemical Name: KS IV
• CAS No.: 121242-02-2
• Molecular Formula: C17H12 O6
• Molecular Weight: 312.279
• Mol file: 121242-02-2.mol

Synonyms:3-Carboxy-6,7-dihydroxy-1-(3',4'-dihydroxyphenyl)-naphthalene

Chemical Property of KS IV

Chemical Property:

• Vapor Pressure: 1.01E-16mmHg at 25°C
• Boiling Point: 629.7°Cat760mmHg
• Flash Point: 348.6°C
• PSA: 118.22000
• Density: 1.6g/cm³
• LogP: 3.02740

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of KS IV

There total 5 articles about KS IV which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4,4'-dihydroxy-3,3'-dimethoxy-9-nor-6',7-cyclolign-7,7'-diene-9'-oic acid → 6,7-dihydroxy-4-(3,4-dihydroxyphenyl)naphthalene-2-carboxylic acid (121242-02-2)

Guidance literature:

With pyridine; aluminum (III) chloride; at 60 ℃; for 20h; Cooling with ice; Inert atmosphere;

DOI:10.3390/molecules24020220

Reference yield: 74.0%

6,7-dimethoxy-4-(3,4-dimethoxyphenyl)naphthalene-2-carboxylic acid (110664-69-2) → 6,7-dihydroxy-4-(3,4-dihydroxyphenyl)naphthalene-2-carboxylic acid (121242-02-2)

Guidance literature:

With boron tribromide; In dichloromethane; for 3h; Heating;

DOI:10.1016/0031-9422(89)80132-3

Reference yield:

methyl-6,7-dimethoxy-4-(3,4-dimethoxyphenyl)naphthalene-2-carboxylate (121242-03-3) → 6,7-dihydroxy-4-(3,4-dihydroxyphenyl)naphthalene-2-carboxylic acid (121242-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / KOH / ethanol / 3 h / Heating

2: 74 percent / BBr₃ / CH₂Cl₂ / 3 h / Heating

With potassium hydroxide; boron tribromide; In ethanol; dichloromethane;

DOI:10.1016/0031-9422(89)80132-3

upstream raw materials:

6,7-dimethoxy-4-(3,4-dimethoxyphenyl)naphthalene-2-carboxylic acid

Cannabisin A

methyl-6,7-dimethoxy-4-(3,4-dimethoxyphenyl)naphthalene-2-carboxylate

Downstream raw materials:

methyl-6,7-dimethoxy-4-(3,4-dimethoxyphenyl)naphthalene-2-carboxylate