5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester

Base Information

• Chemical Name: 5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester
• CAS No.: 1189795-95-6
• Molecular Formula: C₁₆H₁₇NO₃
• Molecular Weight: 271.316
• Mol file: 1189795-95-6.mol

Synonyms:5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester

Chemical Property of 5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester

There total 1 articles about 5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Ethyl 3-bromopropionate (539-74-2) + phenylacetonitrile (140-29-4) → 5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester (1189795-95-6)

Guidance literature:

With sodium amide; In toluene; at 0 ℃; for 6h; Heating;

Reference yield: 83.0%

5-cyano-2-oxo-5-phenyl-cyclohexane carboxylic acid ethyl ester (1189795-95-6) → 4-cyano-4-phenylcyclohexanone (25115-74-6)

Guidance literature:

With hydrogenchloride; In water; acetic acid; for 3.5h; Heating;

upstream raw materials:

Ethyl 3-bromopropionate

phenylacetonitrile

Downstream raw materials:

4-cyano-4-phenylcyclohexanone