N²-(4-tert-butylbenzoyl)-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine

Base Information

• Chemical Name: N²-(4-tert-butylbenzoyl)-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine
• CAS No.: 263841-84-5
• Molecular Formula: C₂₅H₂₇N₃O₃
• Molecular Weight: 417.508
• Mol file: 263841-84-5.mol

Synonyms:N²-(4-tert-butylbenzoyl)-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine

Chemical Property of N²-(4-tert-butylbenzoyl)-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N²-(4-tert-butylbenzoyl)-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine

There total 3 articles about N²-(4-tert-butylbenzoyl)-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N2-[(4-tert-butyl)benzoyl]-N4-tert-butoxycarbonyl-N1-(4-methoxybenzoyl)-1,2,4-benzenetriamine (263841-64-1) → N2-(4-tert-butylbenzoyl)-N1-(4-methoxybenzoyl)-1,2,4-benzenetriamine (263841-84-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h;

DOI:10.1021/jm990326m

Reference yield:

N1-[(4-methoxy)benzoyl]-N4-tert-butoxycarbonyl-2-nitro-1,4-benzenediamine → N2-(4-tert-butylbenzoyl)-N1-(4-methoxybenzoyl)-1,2,4-benzenetriamine (263841-84-5)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Pd/C / tetrahydrofuran

2: pyridine / CH₂Cl₂

3: TFA / CH₂Cl₂ / 5 h / 20 °C

With pyridine; hydrogen; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; 1: Reduction / 2: Acylation / 3: Acidolysis;

DOI:10.1021/jm990326m

Reference yield:

N1-[(4-methoxy)benzoyl]-N4-tert-butoxycarbonyl-1,2,4-benzenetriamine (263841-63-0) → N2-(4-tert-butylbenzoyl)-N1-(4-methoxybenzoyl)-1,2,4-benzenetriamine (263841-84-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂

2: TFA / CH₂Cl₂ / 5 h / 20 °C

With pyridine; trifluoroacetic acid; In dichloromethane; 1: Acylation / 2: Acidolysis;

DOI:10.1021/jm990326m

upstream raw materials:

N²-[(4-tert-butyl)benzoyl]-N⁴-tert-butoxycarbonyl-N¹-(4-methoxybenzoyl)-1,2,4-benzenetriamine

N¹-[(4-methoxy)benzoyl]-N⁴-tert-butoxycarbonyl-1,2,4-benzenetriamine