(5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

Base Information

Chemical Name:(5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester
CAS No.:253155-06-5
Molecular Formula:C₃₅H₄₀Cl₂N₂O₆
Molecular Weight:655.618
Hs Code.:

(5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

Synonyms:(5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

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Chemical Property of (5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

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Technology Process of (5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

There total 1 articles about (5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90741-37-0
(2S)-cis-1-benzyl-5-(carboxymethyl)proline tert-butyl ester

: methyl (2S)-2-amino-3-[4-[(2,6-dichlorophenyl)methoxy]phenyl]propanoate monohydrochloride

: 253155-06-5
(5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

Guidance literature:: With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; for 12h;

Reference yield:

: 253155-06-5
(5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

: 253155-07-6
(5R)-5-[2-[[(1S)-1-Carboxy-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester

Guidance literature:: (5R)-5-[2-[[(1S)-1-Methoxycarbonyl-2-[4-[(2,6-dichlorophenyl)methoxy]phenyl]ethyl]amino]-2-oxoethyl]-1-(phenylmethyl)-L-proline 1,1-Dimethylethyl Ester; With methanol; water; potassium carbonate; for 12h;

With hydrogenchloride; methanol; water;