1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid

Base Information

• Chemical Name: 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid
• CAS No.: 106821-07-2
• Molecular Formula: C₁₃H₂₁N₃O₄Si
• Molecular Weight: 311.413
• Mol file: 106821-07-2.mol

Synonyms:1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid

Chemical Property of 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid

There total 3 articles about 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-<(trimethylsilyl)oxy>phenyl isocyanate (42003-65-6) + ethylhydrazine carboxylate (4114-31-2) → 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid (106821-07-2)

Guidance literature:

In toluene; for 5h; Ambient temperature;

Reference yield:

N-(Trimethylsilyl)-4-(trimethylsiloxy)benzolamin (52726-86-0) → 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid (106821-07-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) chlorotrimethylsilane, triethylamine / 1.) toluene, 1.5 h, heating; 2.) toluene, 2 h, heating

2: 94 percent / toluene / 5 h / Ambient temperature

With chloro-trimethyl-silane; triethylamine; In toluene;

Reference yield:

4-amino-phenol (123-30-8) → 1-(Ethoxycarbonyl)-4-<4-(trimethylsilyloxy)phenyl>semicarbazid (106821-07-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / triethylamine / tetrahydrofuran / 0.5 h / Heating

2: 2.) chlorotrimethylsilane, triethylamine / 1.) toluene, 1.5 h, heating; 2.) toluene, 2 h, heating

3: 94 percent / toluene / 5 h / Ambient temperature

With chloro-trimethyl-silane; triethylamine; In tetrahydrofuran; toluene;

upstream raw materials:

4-<(trimethylsilyl)oxy>phenyl isocyanate

ethylhydrazine carboxylate

N-(Trimethylsilyl)-4-(trimethylsiloxy)benzolamin

4-amino-phenol

Downstream raw materials:

4-(4-Hydroxyphenyl)-1,2,4-triazolin-3,5-dion

8-(4-Hydroxy-3-nitrophenyl)-1,6,8-triazabicyclo<4.3.0>non-3-en-7,9-dion

8-(4-Hydroxyphenyl)-1,6,8-trazabicyclo<4.3.0>non-3-en-7,9-dion

4-(4-Hydroxy-3-nitrophenyl)-1,2,4-triazolin-3,5-dion