1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

Base Information

Chemical Name:1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)
CAS No.:852880-43-4
Molecular Formula:C₂₉H₃₅Cl₂FN₂O₃
Molecular Weight:549.513
Hs Code.:

Synonyms:1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

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Chemical Property of 1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

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Technology Process of 1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

There total 1 articles about 1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 617710-53-9
[1-(3,5-dichlorophenyl)-ethyl]-amine (enantiomer 1)

: 852880-41-2
2-[1-{[(1,1-dimethylethyl)-oxy]-carbonyl}-4-(4-fluorophenyl)-4-piperidinyl]-4-pentenoic acid

: 852880-43-4
1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

Guidance literature:: 2-[1-{[(1,1-dimethylethyl)-oxy]-carbonyl}-4-(4-fluorophenyl)-4-piperidinyl]-4-pentenoic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); for 0.75h;

[1-(3,5-dichlorophenyl)-ethyl]-amine (enantiomer 1); In DMF (N,N-dimethyl-formamide); at 20 ℃; for 14h;

Reference yield:

: 852880-43-4
1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

: 1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-oxopropyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1)

Guidance literature:: 1,1-dimethylethyl 4-[1-({[(3,5-dichlorophenyl)-ethyl]-amino}-carbonyl)-3-buten-1-yl]-4-(4-fluorophenyl)-1-piperidinecarboxylate (chain enantiomer 1); With osmium(VIII) oxide; In tetrahydrofuran; water; at 20 ℃; for 1h;

With sodium periodate; In tetrahydrofuran; water; at 20 ℃; for 1h;