7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel

Base Information

Chemical Name:7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel
CAS No.:1401086-20-1
Molecular Formula:C₅₄H₆₁Cl₂NO₁₆
Molecular Weight:1050.98
Hs Code.:

Synonyms:7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel

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Technology Process of 7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel

There total 1 articles about 7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32981-86-5,172018-16-5
10-deacetylbaccatin III

: 1401086-20-1
7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; pyridine / dichloromethane / 2 h / -5 - 5 °C / Inert atmosphere

2: dmap; diisopropyl-carbodiimide / toluene / 24 h / 8 - 20 °C

With pyridine; dmap; diisopropyl-carbodiimide; In dichloromethane; toluene;

Reference yield:

: 1401086-20-1
7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel

: 632335-31-0
7,10-di-O-(2-chlroacetyl)docetaxel

Guidance literature:: 7,10-di-O-chloroacetyl-2'-O-benzyl docetaxel; With hydrogenchloride; 5%-palladium/activated carbon; In tetrahydrofuran; ethanol; water; for 1h; pH=2 - 4;

With hydrogen; 5%-palladium/activated carbon; In tetrahydrofuran; ethanol; water; under 3878.71 Torr; pH=2 - 4;