Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Base Information

Chemical Name:Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester
CAS No.:511511-39-0
Molecular Formula:C₃₆H₄₇N₃O₁₃
Molecular Weight:729.781
Hs Code.:

Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Synonyms:Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Suppliers and Price of Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

There total 10 articles about Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: ethyl 2,4,6-tri-O-acetyl-3-O-methyl-1-thio-α/β-L-iodopyranose

: 511511-28-7
(2R,3R,4S,5S,6R)-6-(2-Azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-ol

: 511511-39-0
Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Guidance literature:: With N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In 1,4-dioxane; dichloromethane; toluene; at -20 ℃; for 0.5h;
DOI:10.1002/1099-0690(200212)2002:23<3954::AID-EJOC3954>3.0.CO;2-2

Reference yield:

: 145852-76-2
3,6-di-O-benzyl-D-glucal

: 511511-39-0
Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 10 steps

1.1: 75 percent / imidazole / dimethylformamide / 16 h / 60 °C

2.1: 100 percent / dimethyldioxirane / acetone; CH₂Cl₂ / 0.08 h / 0 °C

3.1: 75 percent / ZnCl₂ / tetrahydrofuran; various solvent(s) / 1 h / 0 - 20 °C

4.1: 93 percent / NaH / dimethylformamide / 1 h / 0 °C

5.1: BH₃; 2-methyl-2-butene / tetrahydrofuran / 0.5 h / 0 °C

5.2: NaOH; H₂O₂ / H₂O / 1 h

6.1: 2.66 g / LiAlH₄ / tetrahydrofuran / 0.08 h / 0 °C

7.1: pyridine / CH₂Cl₂ / 16 h

8.1: 0.805 g / NaN₃ / dimethylformamide / 3 h / 60 °C

9.1: 99 percent / tetrabutylammonium fluoride / tetrahydrofuran / 3 h

10.1: 96 percent / N-iodosuccinimide; mol. sieves 4 Angstroem; TfOH / toluene; dioxane; CH₂Cl₂ / 0.5 h / -20 °C

With pyridine; 1H-imidazole; N-iodo-succinimide; lithium aluminium tetrahydride; sodium azide; 2-methyl-but-2-ene; trifluorormethanesulfonic acid; 4 A molecular sieve; borane; tetrabutyl ammonium fluoride; 3,3-dimethyldioxirane; sodium hydride; zinc(II) chloride; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1002/1099-0690(200212)2002:23<3954::AID-EJOC3954>3.0.CO;2-2

Reference yield:

: 253683-41-9
1,5-anhydro-4-O-tert-butyldimethylsilyl-2-deoxy-3,6-di-O-benzyl-D-arabino-hex-1-enitol

: 511511-39-0
Acetic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-6-(2-azido-ethyl)-4-benzyloxy-2-benzyloxymethyl-5-methoxy-tetrahydro-pyran-3-yloxy]-4-methoxy-tetrahydro-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 9 steps

1.1: 100 percent / dimethyldioxirane / acetone; CH₂Cl₂ / 0.08 h / 0 °C

2.1: 75 percent / ZnCl₂ / tetrahydrofuran; various solvent(s) / 1 h / 0 - 20 °C

3.1: 93 percent / NaH / dimethylformamide / 1 h / 0 °C

4.1: BH₃; 2-methyl-2-butene / tetrahydrofuran / 0.5 h / 0 °C

4.2: NaOH; H₂O₂ / H₂O / 1 h

5.1: 2.66 g / LiAlH₄ / tetrahydrofuran / 0.08 h / 0 °C

6.1: pyridine / CH₂Cl₂ / 16 h

7.1: 0.805 g / NaN₃ / dimethylformamide / 3 h / 60 °C

8.1: 99 percent / tetrabutylammonium fluoride / tetrahydrofuran / 3 h

9.1: 96 percent / N-iodosuccinimide; mol. sieves 4 Angstroem; TfOH / toluene; dioxane; CH₂Cl₂ / 0.5 h / -20 °C

With pyridine; N-iodo-succinimide; lithium aluminium tetrahydride; sodium azide; 2-methyl-but-2-ene; trifluorormethanesulfonic acid; 4 A molecular sieve; borane; tetrabutyl ammonium fluoride; 3,3-dimethyldioxirane; sodium hydride; zinc(II) chloride; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1002/1099-0690(200212)2002:23<3954::AID-EJOC3954>3.0.CO;2-2