3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine

Base Information

• Chemical Name: 3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine
• CAS No.: 129206-88-8
• Molecular Formula: C₁₄H₁₇F₃N₂O
• Molecular Weight: 286.297
• Mol file: 129206-88-8.mol

Synonyms:3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine

Chemical Property of 3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine

There total 2 articles about 3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-(Diethyl-hydrazono)-1,1,1-trifluoro-3-p-tolyl-propan-2-one (129206-83-3) → 3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine (129206-88-8)

Guidance literature:

With trifluoroacetic acid; at 25 ℃; for 2h;

DOI:10.1055/s-1990-26916

Reference yield:

N,N-Diethyl-N'-[1-p-tolyl-meth-(E)-ylidene]-hydrazine (129854-01-9) → 3-Ethyl-2-methyl-5-p-tolyl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine (129206-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / 2,6-lutidine / Ambient temperature

2: 97 percent / CF₃COOH / 2 h / 25 °C

With 2,6-dimethylpyridine; trifluoroacetic acid;

DOI:10.1055/s-1990-26916

upstream raw materials:

3-(Diethyl-hydrazono)-1,1,1-trifluoro-3-p-tolyl-propan-2-one

N,N-Diethyl-N'-[1-p-tolyl-meth-(E)-ylidene]-hydrazine