8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid

Base Information

• Chemical Name: 8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid
• CAS No.: 102854-41-1
• Molecular Formula: C₃₀H₃₇N₃O₉
• Molecular Weight: 583.638
• Mol file: 102854-41-1.mol

Synonyms:8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid

Chemical Property of 8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid

There total 1 articles about 8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

benzoyl cyanide (613-90-1) → 8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid (102854-41-1)

Guidance literature:

In pyridine; dichloromethane; at 3 ℃; for 25h;

DOI:10.1016/0008-6215(85)85005-9

Reference yield: 45.0%

8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid (102854-41-1) + 1,2,4,6-tetra-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-galactopyranose (102919-01-7) → 8-Methoxycarbonyloctyl-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-O-(2,4,6-tri-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid (102854-42-2)

Guidance literature:

With 4 A molecular sieve; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; for 5h; Ambient temperature;

DOI:10.1016/0008-6215(85)85005-9

Reference yield:

8-Methoxycarbonyloctyl-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid (102854-41-1) → 8-Methoxycarbonyloctyl-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-O-(2,4,6-tri-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / molecular sieve 4A / trimethylsilyl triflate / CH₂Cl₂ / 5 h / Ambient temperature

2: 1.) NiCl_2.6H₂O, 2percent H₃BO₃, NaBH₄ / 1.) ethanol, r.t., 1 h, 2.) r.t., 4 h

With sodium tetrahydroborate; 4 A molecular sieve; boric acid; nickel dichloride; trimethylsilyl trifluoromethanesulfonate; In dichloromethane;

DOI:10.1016/0008-6215(85)85005-9

upstream raw materials:

benzoyl cyanide

Downstream raw materials:

8-Methoxycarbonyloctyl-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-O-(2,4,6-tri-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosid